Article
Glycosylation of tissue factor is not essential for its transport or functions.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2011
Kothari H, Rao L V M, Pendurthi U R
Abstract excerpt
BACKGROUND: Glycosylation plays an important role in protein function. The importance of glycosylation for tissue factor (TF) function is unclear. OBJECTIVE: The aim of the present study is to investigate the importance of TF glycosylation in transport to the cell surface and its coagulant and signaling functions. METHODS: Endothelial cells and peripheral blood mononuclear cells (PBMC) were treated with...
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