Article
Hypermethylation in histologically distinct classes of breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2004
Bae Young Kyung, Brown Amy, Garrett Elizabeth, Bornman Daniel, Fackler Mary Jo, Sukumar Saraswati, Herman James G, Gabrielson Edward
Abstract excerpt
PURPOSE: A number of different genes are known to be inactivated by aberrant hypermethylation in breast cancer, but it is still unknown to what extent these epigenetic alterations differ according to specific breast cancer phenotypes. We sought to determine whether the extent of hypermethylation or defined profiles of gene hypermethylation are associated with biological characteristics of breast cancers....
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