Article
DNA methylation epigenotypes in breast cancer molecular subtypes.
Breast cancer research : BCR - 1 Jan 2010
Bediaga Naiara G, Acha-Sagredo Amelia, Guerra Isabel, Viguri Amparo, Albaina Carmen, Ruiz Diaz Irune, Rezola Ricardo, Alberdi María Jesus, Dopazo Joaquín, Montaner David, Renobales Mertxe, Fernández Agustín F, Field John K, Fraga Mario F, Liloglou Triantafillos, de Pancorbo Marian M
Abstract excerpt
INTRODUCTION: Identification of gene expression based breast cancer subtypes is considered as a critical means of prognostication. Genetic mutations along with epigenetic alterations contribute to gene expression changes occurring in breast cancer. So far, these epigenetic contributions to sporadic breast cancer subtypes have not been well characterized, and there is only a limited understanding of the epigenetic...
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