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Omeprazole treatment of Korean patients: effects on gastric pH and gastrin release in relation to CYP2C19 geno- and phenotypes.

Basic & clinical pharmacology & toxicology - 1 Sept 2004

Roh Hyung-Keun, Kim Pum-Soo, Lee Don-Haeng, Tybring Gunnel, Sagar Mohamed, Park Chang-Shin, Seensalu Rein, Bertilsson Leif

Abstract excerpt

This study aimed to investigate the effect of omeprazole on intragastric pH and gastrin release as well as the plasma concentration of omeprazole in relation to CYP2C19 genotypes after repeated doses in Korean patients. Twenty-six Korean patients with acid related disease were genotyped for CYP2C19 by allele specific PCR (wt/wt, CYP2C19*1/*1; wt/mut, CYP2C19*1/*2 or *1/*3; mut/mut, CYP2C19*2/*2, *2/*3 or *3/*3)....

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Identifiers

PMID: 15447734
DOI: 10.1111/j.1742-7843.2004.950302.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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