Competitive inhibition of lipolytic enzymes. VI. Inhibition of two human phospholipases A2 by acylamino phospholipid analogues.

doi:10.1016/0005-2760(92)90127-h

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Article

Competitive inhibition of lipolytic enzymes. VI. Inhibition of two human phospholipases A2 by acylamino phospholipid analogues.

Biochimica et biophysica acta - 20 Feb 1992

van den Berg L, Franken P A, Verheij H M, Dijkman R, de Haas G H

Abstract excerpt

The competitive inhibition of human pancreatic and a mutant human platelet phospholipase A2 (PLA2) was investigated using acylamino phospholipid analogues, which are potent competitive inhibitors of porcine pancreatic PLA2 [De Haas et al. (1990) Biochim. Biophys. Acta 1046, 249-257]. Both the mut...

Topics

Binding, Competitive
Blood Platelets
Humans
Mutation
Pancreas
Phospholipases A
Phospholipases A2
Phospholipids

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