DNA typing in hereditary disease.

Abstract excerpt

An increasing number of hereditary diseases are becoming amenable to diagnosis by analysis of DNA as the responsible genes are located and identified. Gel electrophoresis of DNA fragments plays a central role in the diagnosis of hereditary disease. Electrophoretic separation of differently sized fragments enables the characterization or typing of normal variants which are known to be genetically linked to disease...

Topics

• Base Sequence
• DNA
• Genetic Diseases, Inborn
• Genetic Markers
• Humans
• Molecular Sequence Data
• Mutation
• Polymorphism, Restriction Fragment Length