Article
Development of a simple multiplex polymerase chain reaction for the simultaneous detection of factor V Leiden and prothrombin 20210A mutations.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology - 1 Sept 1999
Dubreuil Lastrucci R M, Dawson D A, Bowden J H, Marion Münster M
Abstract excerpt
BACKGROUND: The demand for thrombophilia testing at the molecular level is increasing, and consequently, the work load of the routine molecular laboratory is also increasing. Efforts to lighten the work load, economize on time, and strive for reduced costs while still maintaining quality assurance are thus necessary. METHODS AND RESULTS: A multiplex polymerase chain reaction (PCR) for the detection of factor V...
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