Article
Roles of Listeria monocytogenes virulence factors in survival: virulence factors distinct from listeriolysin are needed for the organism to survive an early neutrophil-mediated host defense mechanism.
Infection and immunity - 1 Mar 1992
Conlan J W, North R J
Abstract excerpt
Avirulent mutant strains of Listeria monocytogenes which fail to produce phosphatidylinositol-specific phospholipase C, or which produce reduced amounts of hemolytic listeriolysin O, are incapable of causing progressive infection in normal mice. However, both strains can grow progressively in mic...
Topics
- Animals
- Bacterial Toxins
- Female
- Heat-Shock Proteins
- Hemolysin Proteins
- Lethal Dose 50
- Listeria monocytogenes
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mutation
- Neutrophils
- Type C Phospholipases
- Virulence