Article
Role of the transmembrane and cytoplasmic domains in the assembly and surface exposure of the platelet integrin GPIIb/IIIa.
Biochemistry - 3 Mar 1992
Frachet P, Duperray A, Delachanal E, Marguerie G
Abstract excerpt
Integrins are alpha beta heterodimers that play a major role in cell-cell contacts and in interactions between cells and extracellular matrices. Identification of structural domains that are critical for the expression of such receptors at the cell surface in a functional conformation is one of t...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Cell Membrane
- Chlorocebus aethiops
- Cytoplasm
- Gene Expression
- Humans
- Molecular Sequence Data
- Mutation
- Plasmids
- Platelet Membrane Glycoproteins