Article
Diabetes mellitus in adults: association of HLA DRB1 and DQB1 diabetes risk alleles with GADab presence and C-peptide secretion.
Immunology letters - 1 Sept 2004
Novota Peter, Cerna Marie, Kolostova Katarina, Cejkova Pavlina, Zdarsky Emanuel, Novakova Dana, Kucera Petr, Novak Jan, Andel Michal
Abstract excerpt
In our study, we investigated the relationship of HLA class II alleles to antibody production against glutamic acid decarboxylase (GADab) and to C-peptide secretion (CP) in diabetic patients. A group of 334 patients (190 women) diagnosed after 35 years of age and 99 control subjects were studied. Patients were divided into four groups according to concentrations of CP and GADab, respectively (CP high/low, GADab...
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