Article
Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population.
The Australian & New Zealand journal of obstetrics & gynaecology - 1 Oct 2004
Yilmaz Hülya, Unlüçerçi Yesim, Gürdöl Figen, Isbilen Elif, Isbir Turgay
Abstract excerpt
BACKGROUND: Hyperhomocysteinaemia is a common finding in a wide variety of pathological conditions that exhibit endothelial disturbances. In the pathogenesis of pre-eclampsia, endothelial cell activation or dysfunction has been proposed as a central feature, and the presence of hyperhomocysteinaemia in varying degrees has been detected. One of the known causes of hyperhomocysteinaemia is polymorphism in the...
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