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Article

Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathies.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2011

Klai Sarra, Fekih-Mrissa Najiba, El Housaini Sonia, Kaabechi Naziha, Nsiri Brahim, Rachdi Radhouen, Gritli Nasredine

Abstract excerpt

Our aim in this study was to investigate the association between elevated homocysteine levels and the two MTHFR polymorphisms, C677T and A1298C, with several pregnancy complications such as recurrent pregnancy loss, preeclampsia, placental abruption and intrauterine growth retardation. In 203 women with different placental vasculopathies, we determined the MTHFR C677T and the A1298C prevalence and their relative...

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PMID: 21577095
DOI: 10.1097/MBC.0b013e328344f80f

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MTHFR

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