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Article

A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains.

Nature - 5 Mar 1992

Chenevert J, Corrado K, Bender A, Pringle J, Herskowitz I

Abstract excerpt

Cell polarization requires that a cellular axis or cell-surface site be chosen and that the cytoskeleton be organized with respect to it. Details of the link between the cytoskeleton and the chosen axis or site are not clear. Cells of the yeast Saccharomyces cerevisiae exhibit cell polarization in two phases of their life cycle, during vegetative growth and during mating, which reflects responses to intracellular...

Topics

Adaptor Proteins, Signal Transducing
Amino Acid Sequence
Base Sequence
Cell Polarity
Fungal Proteins
Molecular Sequence Data
Mutation
Restriction Mapping
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Alignment

Source

Identifiers

PMID: 1538785
DOI: 10.1038/356077a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1538785-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Click a neighbor to travelStep 1 · 12 closest

A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains.PMID 1538785Read ↗

Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae.Semantic proximity Read ↗

FAR1 is required for oriented polarization of yeast cells in response to mating pheromones.Semantic proximity Read ↗

Pheromone response in yeast: association of Bem1p with proteins of the MAP kinase cascade and actin.Semantic proximity Read ↗

Discovering the poles in yeast.Semantic proximity Read ↗

A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization.Semantic proximity Read ↗

Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated yeast pheromone signalling pathway to regulators of cell polarity.Semantic proximity Read ↗

A small conserved domain in the yeast Spa2p is necessary and sufficient for its polarized localization.Semantic proximity Read ↗

The Glc7p-interacting protein Bud14p attenuates polarized growth, pheromone response, and filamentous growth in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of cell polarity by interactions of Msb3 and Msb4 with Cdc42 and polarisome components.Semantic proximity Read ↗

Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase.Semantic proximity Read ↗

PAK-family kinases regulate cell and actin polarization throughout the cell cycle of Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of polarized growth initiation and termination cycles by the polarisome and Cdc42 regulators.Semantic proximity Read ↗

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