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Article

A Small Ras-like protein Ray/Rab1c modulates the p53-regulating activity of PRPK.

Biochemical and biophysical research communications - 26 May 2006

Abe Yasuhito, Takeuchi Takashi, Imai Yoshinori, Murase Ryuichi, Kamei Yoshiaki, Fujibuchi Taketsugu, Matsumoto Suguru, Ueda Norifumi, Ogasawara Masahito, Shigemoto Kazuhiro, Kito Katsumi

Abstract excerpt

PRPK phosphorylates serine-15 residue of p53 and enhances transcriptional activity. PRPK possesses a bipartite nuclear localization signal and localizes in nucleus when over-expressed in cells. However, intrinsic PRPK localizes mainly in the cytosol in situ. While studying the mechanisms in the d...

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PMID: 16600182
DOI: 10.1016/j.bbrc.2006.03.071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16600182-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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