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Article

Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms.

Therapeutic drug monitoring - 1 Oct 2004

Hung Chin-Chuan, Lin Chun-Jung, Chen Chih-Chuan, Chang Chee-Jen, Liou Horng-Huei

Abstract excerpt

To search for the optimal dosage of phenytoin in patients with epilepsy based on the metabolic activities of CYP2C9 and CYP2C19 polymorphisms, a total of 169 patients receiving phenytoin treatment for more than 1 month were recruited. Phenytoin concentration, serum albumin, liver function tests, and renal function tests were measured. CYP2C9 and CYP2C19 polymorphisms were genotyped by PCR-RFLP analysis, and...

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Source

Identifiers

PMID: 15385837
DOI: 10.1097/00007691-200410000-00012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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