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Inbred Mouse Models in Cryptococcus neoformans Research

17 Jun 2024

Abstract excerpt

Animal models are frequently used as surrogates to understand human disease. In the fungal pathogen Cryptococcus species complex, several variations of a mouse model of disease were developed that recapitulate different aspects of human disease. These mouse models have been implemented using various inbred and outbred mouse backgrounds, many of which have genetic differences that can influence host response and...

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PMID: 38921412
DOI: 10.3390/jof10060426

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