Article
Regulation of myosin light chain phosphorylation by RhoB in neuronal cells.
Experimental cell research - 15 Oct 2004
Conway A-M, James A B, O'Kane E M, Rakhit S, Morris B J
Abstract excerpt
The phosphorylation of myosin light chain (MLC) is a key regulatory point in the control of cellular morphology. Evidence suggests that RhoA-a member of the Rho GTPase family-regulates MLC phosphorylation via Rho kinase (ROK). Neurones display subtle alterations in their cytoarchitecture during the synaptic plasticity following high-frequency stimulation. We have recently demonstrated that RhoB, and not RhoA, is...
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