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Frequency and genetic characterization of multidrug-resistant mutants of Staphylococcus aureus after selection with individual antiseptics and fluoroquinolones.

Biological & pharmaceutical bulletin - 1 Sept 2002

Noguchi Norihisa, Tamura Maki, Narui Koji, Wakasugi Kazunori, Sasatsu Masanori

Abstract excerpt

The frequency of generation of multidrug-resistant mutants of Staphylococcus aureus was examined by selection with various antiseptics and fluoroquinolones and the mutated genes were characterized. Multidrug-resistant mutants with mutation of the region between the promoter and structural regions of the norA gene were generated more frequently during selective pressure with antiseptics than during selective...

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PMID: 12230102
DOI: 10.1248/bpb.25.1129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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