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Article

Role of reactive oxygen species in the induction of apoptosis by α‐tocopheryl succinate

16 Jun 2004

Abstract excerpt

Alpha-tocopheryl succinate (TOS), a vitamin E analog, is a promising anticancer agent due to its abilities to inhibit proliferation and to induce apoptosis in a variety of human malignant cell lines, while being relatively less active toward normal cells. However, the molecular mechanisms underlying the apoptotic effects of TOS are not precisely understood. Reports that TOS can generate reactive oxygen species...

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Share to Antioxidant Activity and Oxidative Stress
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PMID: 15382062
DOI: 10.1002/ijc.20424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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