Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells

1 Dec 2014

Abstract excerpt

BACKGROUND: Tocotrienols, especially the gamma isomer was discovered to possess cytotoxic effects associated with the induction of apoptosis in numerous cancers. Individual tocotrienol isomers are believed to induce dissimilar apoptotic mechanisms in different cancer types. This study was aimed to compare the cytotoxic potency of alpha-, gamma- and delta-tocotrienols, and to explore their resultant apoptotic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidant Activity and Oxidative Stress

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25480449
DOI: 10.1186/1472-6882-14-469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cellsPMID 25480449Read ↗

Tocotrienols Modulate a Life or Death Decision in CancersSemantic proximity Read ↗

Anticancer activities of tocotrienols: A Systematic Scoping ReviewSemantic proximity Read ↗

Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell linesSemantic proximity Read ↗

Beta-Tocotrienol Exhibits More Cytotoxic Effects than Gamma-Tocotrienol on Breast Cancer Cells by Promoting Apoptosis via a P53-Independent PI3-Kinase Dependent PathwaySemantic proximity Read ↗

Targeting Apoptotic Pathway of Cancer Cells with Phytochemicals and Plant-Based NanomaterialsSemantic proximity Read ↗

Vitamin E and cancer: An insight into the anticancer activities of vitamin E isomers and analogsSemantic proximity Read ↗

γ-Tocotrienol induces mitochondria-mediated apoptosis in human gastric adenocarcinoma SGC-7901 cellsSemantic proximity Read ↗

Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(<scp>ADP</scp>‐ribose) polymerase cleavage and inhibiting nuclear factor kappa‐B activitySemantic proximity Read ↗

The Application of Natural Products in Cancer Therapy by Targeting Apoptosis PathwaysSemantic proximity Read ↗

Chemotherapeutic Approaches for Targeting Cell Death PathwaysSemantic proximity Read ↗

Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeuticsSemantic proximity Read ↗

Evidence of<i>γ</i>-Tocotrienol as an Apoptosis-Inducing, Invasion-Suppressing, and Chemotherapy Drug-Sensitizing Agent in Human Melanoma CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.