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<i>N</i>‐acetyl‐<scp>L</scp>‐cysteine inhibits bleomycin induced apoptosis in malignant testicular germ cell tumors

5 Feb 2013

Abstract excerpt

Antioxidants may prevent apoptosis of cancer cells via inhibiting reactive oxygen species (ROS). However, to date no study has been carried out to elucidate the effects of strong antioxidant N-acetylcysteine (NAC) on Bleomycin induced apoptosis in human testicular cancer (NTERA-2, NT2) cells. For this reason, we studied the effects of Bleomycin and NAC alone and in combination on apoptotic signaling pathways in...

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PMID: 23386420
DOI: 10.1002/jcb.24510

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