Article
Analysis of protein folding and function using backbone modified proteins.
Bioorganic chemistry - 1 Oct 2004
Yang Xiaoye, Wang Min, Fitzgerald Michael C
Abstract excerpt
With the recent development of chemical and biological methods to introduce backbone modifications into the polypeptide chains of proteins, there have been a growing number of site-directed mutagenesis experiments focused on understanding the role of the polypeptide backbone in protein folding and function. The substitution of a main chain amide bond with an ester bond is now a popular mutation to investigate the...
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