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Article

A case of infantile acute lymphoblastic leukemia presenting with rearrangement of MLL at 11q23 and apparent insertion or translocation at 10p12.

Cancer genetics and cytogenetics - 1 Oct 2004

Tirado C A, Lager J, Rosoff P M, Golembiski-Ruiz V, Gong J Z, Goodman B K

Abstract excerpt

We report the case of an 11-month-old patient with a clinical diagnosis of infantile acute lymphoblastic leukemia and an MLL (11q23) rearrangement in 69% of nuclei, revealed with interphase fluorescence in situ hybridization (FISH). Routine chromosome analysis of the bone marrow showed a very subtle rearrangement involving the short arm of chromosome 10 and the long arm of chromosome 11 in the abnormal cells. To...

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Share to Chromosomes, Human, Pair 10
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Translocation, Genetic

Source

Identifiers

PMID: 15381373
DOI: 10.1016/j.cancergencyto.2004.01.018

Genes

MLLT10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A case of infantile acute lymphoblastic leukemia presenting with rearrangement of MLL at 11q23 and apparent insertion or translocation at 10p12.PMID 15381373Read ↗

Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcomeSemantic proximity Read ↗

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Rearrangement of the MLL Gene in Acute Lymphoblastic and Acute Myeloid Leukemias with 11q23 Chromosomal TranslocationsSemantic proximity Read ↗

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Chromosomal Aberration of the 11q23 Locus in Acute Leukemia and Frequency ofMLLGene TranslocationSemantic proximity Read ↗

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