Article
Polymorphisms in the DNA repair gene XPD and susceptibility to esophageal squamous cell carcinoma.
Cancer genetics and cytogenetics - 1 Oct 2004
Yu Hong-Ping, Wang Xiao-Li, Sun Xi, Su Yan-Hua, Wang You-Jie, Lu Bin, Shi Lu-Yuan, Xiong Chun-lan, Li Yuan-Yuan, Li Fang, Xu Shun-Qing
Abstract excerpt
Polymorphisms of the nucleotide excision repair gene XPD are candidates for influencing cancer susceptibility. To determine the effect of XPD genetic polymorphisms on the risk of esophageal squamous cell carcinoma (ESCC) and its interaction with carcinogen exposure, XPD polymorphisms at codon 312 (Asp-->Asn) and codon 751 (Lys-->Gln) were determined in 135 ESCC patients and 152 normal controls. Polymorphism at...
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