Article
Significant association of XPD codon 312 single nucleotide polymorphism with bladder cancer susceptibility in Taiwan.
Anticancer research - 1 Oct 2009
Chang Chao-Hsiang, Wang Rou-Fen, Tsai Ru-Yin, Wu Hsi-Chin, Wang Chung-Hsing, Tsai Chia-Wen, Chang Chia-Lin, Tsou Yung-An, Liu Chiu-Shong, Bau Da-Tian
Abstract excerpt
BACKGROUND: The DNA repair gene xeroderma pigmentosum group D (XPD), an important caretaker of the overall genome stability, is thought to play a major role in the development of human malignancy. Polymorphic variants of XPD, at codon 312 (rs1799793), 751 (rs13181) and promoter-114 (rs3810366), were chosen to be studied for their association with bladder cancer susceptibility in a central Taiwanese population....
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