Article
Contribution of DNA Repair Xeroderma Pigmentosum Group D Genotype to Gastric Cancer Risk in Taiwan.
Anticancer research - 1 Sept 2015
Ji Hong-Xue, Chang Wen-Shin, Tsai Chia-Wen, Wang Ju-Yu, Huang Nai-Kuei, Lee An-Sheng, Shen Ming-Yi, Chen Wei-Yu, Chiang Yao-Chang, Shih Tzu-Ching, Hsu Chin-Mu, Bau Da-Tian
Abstract excerpt
AIM: It has been proposed that genetic variations of DNA repair genes confer susceptibility to cancer, and the DNA repair gene xeroderma pigmentosum group D (XPD), the caretaker of genome stability, is thought to play a major role in the nucleotide excision repair system. We investigated three genotypes of XPD, at promoter -114 (rs3810366), and codon 312 (rs1799793), 751 (rs13181), and their associated with...
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