Article
Thyroid hormone receptor isoforms are sequentially expressed in oligodendrocyte lineage cells during rat cerebral development.
Journal of neuroscience research - 1 Dec 1998
Carré J L, Demerens C, Rodríguez-Peña A, Floch H H, Vincendon G, Sarliève L L
Abstract excerpt
In the mammalian brain, thyroid hormones regulate myelination. Their actions are mediated by interactions with nuclear receptors that function as ligand-regulated transcription factors. Two genes, alpha and beta, encode different isoforms, of which only the beta and alpha1 isoforms are authentic nuclear triiodothyronine (T3)-receptors (NT3R). In agreement with the important role of T3 on myelination and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
