Article
Connective tissue growth factor (CTGF/CCN2): a protagonist in cardiac allograft vasculopathy development?
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Aug 2012
Pantou Malena P, Manginas Athanasios, Alivizatos Peter A, Degiannis Dimitrios
Abstract excerpt
BACKGROUND: Connective tissue growth factor (CTGF) has been reported to be upregulated in experimental models of chronic cardiac allograft rejection. We investigated the contribution of CTGF to the development of cardiac allograft vasculopathy (CAV), a surrogate marker for chronic rejection. METHODS: This prospective study included 72 adult heart allograft recipients. Genotyping of the rs6918698 polymorphism was...
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