Article
Transforming growth factor-beta polymorphisms and cardiac allograft rejection.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Oct 2009
Benza Raymond L, Coffey Christopher S, Pekarek Dawn M, Barchue Joseph P, Tallaj Jose A, Passineau Michael J, Grenett Hernan E
Abstract excerpt
BACKGROUND: Cytokine gene polymorphisms regulate cytokine expression. We analyzed transforming growth factor-beta (TGF-beta) allelic variation in codon 25 in susceptibility to acute rejection episodes in cardiac transplant recipients. METHODS: Between June 1997 and December 2001, 123 de novo heart transplants were performed at UAB with analysis based on 109 patients. Clinical and laboratory data were recorded at...
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