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Article

DNaseI in pathogenesis of systemic lupus erythematosus.

Clinical immunology (Orlando, Fla.) - 1 Oct 2004

Tsukumo Shin-Ichi, Yasutomo Koji

Abstract excerpt

The aberrant activation of lymphocytes causes autoimmune diseases. Although there are many candidate molecules that are involved in the pathogenesis of autoimmune diseases, it still remains unclear how immunological tolerance is disturbed in each autoimmune disease. Recently, we discovered two patients suffering from systemic lupus erythematosus (SLE) with a defect in the DNaseI gene locus. According to...

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PMID: 15380524
DOI: 10.1016/j.clim.2004.05.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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