Article
CARD15 mutations in patients with plaque-type psoriasis and psoriatic arthritis: lack of association.
Archives of dermatological research - 1 Mar 2006
Jenisch Stefan, Hampe Jochen, Elder James T, Nair Rajan, Stuart Phil, Voorhees John J, Schreiber Stefan, Kabelitz Dietrich, Christophers Enno, Weichenthal Michael
Abstract excerpt
Psoriasis has a strong genetic component in the development of the disease as indicated by familial occurrence and a high concordance rate among monozygotic twins. In genome-wide scans for psoriasis several susceptibility loci have been detected, but the disease-causing genes have not yet been identified. A recent scan, performed on psoriatic arthritis (PsA), which occurs in about 15% of the psoriasis patients...
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