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Article

Hypermethylation of the RASSF1A tumor suppressor gene in Japanese clear cell renal cell carcinoma.

Oncology reports - 1 Oct 2004

Tokinaga Kenji, Okuda Heiwa, Nomura Asuka, Ashida Shingo, Furihata Mutsuo, Shuin Taro

Abstract excerpt

Hypermethylation associated inactivation of RASSF1A tumor suppressor gene at chromosome 3p21.3 has been observed in several human malignancies. Relatively high (91%) or low (23%) frequencies were reported in the methylation status of promoter region of the RASSF1A gene in clear cell renal carcinoma (RCC) depending on the country the report was from. To clarify exact contribution of the hypermethylation of RASSF1A...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15375503

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hypermethylation of the RASSF1A tumor suppressor gene in Japanese clear cell renal cell carcinoma.PMID 15375503Read ↗

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