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Article

The candidate tumor suppressor gene, <i>RASSF1A</i> , from human chromosome 3p21.3 is involved in kidney tumorigenesis

5 Jun 2001

Abstract excerpt

Clear cell-type renal cell carcinomas (clear RCC) are characterized almost universally by loss of heterozygosity on chromosome 3p, which usually involves any combination of three regions: 3p25-p26 (harboring the VHL gene), 3p12-p14.2 (containing the FHIT gene), and 3p21-p22, implying inactivation of the resident tumor-suppressor genes (TSGs). For the 3p21-p22 region, the affected TSGs remain, at present, unknown....

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PMID: 11390984
DOI: 10.1073/pnas.131216298

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The candidate tumor suppressor gene, <i>RASSF1A</i> , from human chromosome 3p21.3 is involved in kidney tumorigenesisPMID 11390984Read ↗

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