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Article

Promoter Hypermethylation Profile of Kidney Cancer

15 Jun 2004

Abstract excerpt

PURPOSE: Promoter hypermethylation is an important mechanism of inactivation of tumor suppressor genes in cancer cells. Kidney tumors are heterogeneous in their histology, genetics, and clinical behavior. To gain insight into the role of epigenetic silencing of tumor suppressor and cancer genes in kidney tumorigenesis, we determined a hypermethylation profile of kidney cancer. EXPERIMENTAL DESIGN: We examined the...

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Share to Epigenetics and DNA Methylation
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PMID: 15217927
DOI: 10.1158/1078-0432.ccr-04-0175

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