Article
Identification of Novel Epigenetic Markers for Clear Cell Renal Cell Carcinoma
19 Jul 2008
Abstract excerpt
PURPOSE: We identified significantly hypermethylated genes in clear cell renal cell carcinoma. MATERIALS AND METHODS: We previously identified a set of under expressed genes in renal cell carcinoma tissue through transcriptional profiling and a robust computational screen. We selected 19 of these genes for hypermethylation analysis using a rigorous search for the best candidate regions, considering CpG islands...
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