Evaluation of allelic alterations in short tandem repeats in different kinds of solid tumors--possible pitfalls in forensic casework.

doi:10.1016/j.forsciint.2004.03.006

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Article

Evaluation of allelic alterations in short tandem repeats in different kinds of solid tumors--possible pitfalls in forensic casework.

Forensic science international - 4 Oct 2004

Poetsch Micaela, Petersmann Astrid, Woenckhaus Christian, Protzel Chris, Dittberner Thomas, Lignitz Eberhard, Kleist Britta

Abstract excerpt

Archival pathology specimens are nowadays a frequently used source in forensic identification or paternity testing, if no other material is available. A greater part of this archived material, however, consists of solid tumors known for aberrations in coding and non-coding regions of the genome. Therefore, alterations of short tandem repeats (STRs) used in forensic casework are also possible. In our study of 118...

Topics

Alleles
Allelic Imbalance
DNA Fingerprinting
Genomic Instability
Humans
Neoplasms
Polymerase Chain Reaction
Tandem Repeat Sequences

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PMID: 15374588
DOI: 10.1016/j.forsciint.2004.03.006

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