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Article

The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance‐associated protein family

16 Sept 2004

Abstract excerpt

ATP-binding cassette (ABC) transporters are involved in the transport of substrates across biological membranes and are essential for many cellular processes. Of the fifty-six Drosophila ABC transporter genes only white, brown, scarlet, E23 and Atet have been studied in detail. Phylogenetic analyses identify the Drosophila gene dMRP/CG6214 as an orthologue to the human multidrug-resistance associated proteins...

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PMID: 15373810
DOI: 10.1111/j.0962-1075.2004.00512.x

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