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Article

[Genetic and pharmacological effects on prefrontal cortical function in schizophrenia].

Der Nervenarzt - 1 Sept 2004

Heinz Andreas, Braus Dieter F, Romero Berenice, Gallinat Jürgen, Puls Imke, Juckel Georg, Weinberger Daniel R

Abstract excerpt

Brain imaging studies with PET, SPECT, functional magnetic resonance imaging, and spectroscopy provide evidence of prefrontal dysfunction in schizophrenia. Dysfunction of the prefrontal cortex is associated with cognitive impairment and negative symptoms. Combined multimodal imaging shows that a developmentally early disturbance of frontotemporal-limbic neuronal networks is associated with a disinhibition of...

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PMID: 15372159
DOI: 10.1007/s00115-004-1713-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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