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Article

Impact of Familial Loading on Prefrontal Activation in Major Psychiatric Disorders: A Near-Infrared Spectroscopy (NIRS) Study.

Scientific reports - 15 Mar 2017

Ohi Kazutaka, Shimada Takamitsu, Kihara Hiroaki, Yasuyama Toshiki, Sawai Kazuyuki, Matsuda Yukihisa, Oshima Kazuaki, Okubo Hiroaki, Nitta Yusuke, Uehara Takashi, Kawasaki Yasuhiro

Abstract excerpt

Family history (FH) is predictive of the development of major psychiatric disorders (PSY). Familial psychiatric disorders are largely a consequence of genetic factors and typically exhibit more severe impairments. Decreased prefrontal activity during verbal fluency testing (VFT) may constitute an intermediate phenotype for PSY. We investigated whether familial PSY were associated with a greater severity of...

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Identifiers

PMID: 28295013
DOI: 10.1038/srep44268
PMCID: PMC5353718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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