Article
Interference of pathway specific transcription factors.
Biochimica et biophysica acta - 11 Feb 1992
Ponta H, Cato A C, Herrlich P
Abstract excerpt
A mechanism for reversibility of cellular decisions, e.g., proliferation or differentiation, is mediated by direct interference of pathway-specific transcription factors. Due to the relative activity of the transcription factors, genetic programs are reversibly switched on and off. In the case of the transcription factors AP-1 and the family of steroid hormone receptors (including retinoic acid receptor, thyroid...
Topics
- Amino Acid Sequence
- Amino Acids
- DNA-Binding Proteins
- Molecular Sequence Data
- Mutation
- Receptors, Glucocorticoid
- Transcription Factors