Article
A common intermediary factor (p52/54) recognizing "acidic blob"-type domains is required for transcriptional activation by the Jun proteins.
Molecular and cellular biology - 1 Dec 1992
Oehler T, Angel P
Abstract excerpt
The ability of the c-Jun protein, the main component of the transcription factor AP1, to interact directly or indirectly with the RNA polymerase II-initiation complex to activate transcription was investigated by in vivo transcription interference ("squelching") experiments. Coexpression of a Jun...
Topics
- Base Sequence
- DNA
- Gene Expression Regulation
- Hydrogen-Ion Concentration
- Molecular Sequence Data
- Mutation
- Neoplastic Stem Cells
- Oncogene Protein p65(gag-jun)
- Proto-Oncogene Proteins c-jun
- Transcription Factors
- Transcription, Genetic
- Transcriptional Activation
- Tumor Cells, Cultured