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Article

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

Journal of cell science - 1 Oct 2004

Young Daniel W, Zaidi Sayyed K, Furcinitti Paul S, Javed Amjad, van Wijnen Andre J, Stein Janet L, Lian Jane B, Stein Gary S

Abstract excerpt

Regulatory machinery for replication and gene expression is punctately organized in supramolecular complexes that are compartmentalized in nuclear microenvironments. Quantitative approaches are required to understand the assembly of regulatory machinery within the context of nuclear architecture and to provide a mechanistic link with biological control. We have developed 'intranuclear informatics' to quantify...

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PMID: 15367579
DOI: 10.1242/jcs.01229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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