Article
Comparison of amplification enzymes for Hepatitis C Virus quasispecies analysis.
Virology journal - 22 Apr 2005
Polyak Stephen J, Sullivan Daniel G, Austin Michael A, Dai James Y, Shuhart Margaret C, Lindsay Karen L, Bonkovsky Herbert L, Di Bisceglie Adrian M, Lee William M, Morishima Chihiro, Gretch David R
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) circulates as quasispecies (QS), whose evolution is associated with pathogenesis. Previous studies have suggested that the use of thermostable polymerases without proofreading function may contribute to inaccurate assessment of HCV QS. In this report, we compar...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
