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Article

Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro.

The Journal of biological chemistry - 26 Nov 2004

Necula Mihaela, Kuret Jeff

Abstract excerpt

Alzheimer's disease is defined in part by the intraneuronal aggregation of tau protein into filamentous lesions. The pathway is accompanied by posttranslational modifications including phosphorylation and glycation, each of which has been shown to promote tau fibrillization in vitro when present...

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Source

Identifiers

PMID: 15364924
DOI: 10.1074/jbc.M405527200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15364924-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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