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Article

Alternative splicing after gene duplication drives CEACAM1-paralog diversification in the horse.

BMC evolutionary biology - 15 Mar 2018

Mißbach Sophie, Aleksic Denis, Blaschke Lisa, Hassemer Timm, Lee Kyung Jin, Mansfeld Martin, Hänske Jana, Handler Johannes, Kammerer Robert

Abstract excerpt

BACKGROUND: The CEA gene family is one of the most rapidly evolving gene families in the human genome. The founder gene of the family is thought to be an ancestor of the inhibitory immune checkpoint molecule CEACAM1. Comprehensive analyses of mammalian genomes showed that the CEA gene family is subject to tremendous gene family expansion and contraction events in different mammalian species. While in some species...

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Source

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Identifiers

PMID: 29544443
DOI: 10.1186/s12862-018-1145-x
PMCID: PMC5856374

Genes

CEACAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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