Article
Two medium-chain acyl-coenzyme A synthetase genes, SAH and MACS1, are associated with plasma high-density lipoprotein cholesterol levels, but they are not associated with essential hypertension.
Journal of hypertension - 1 Oct 2004
Haketa Akira, Soma Masayoshi, Nakayama Tomohiro, Sato Mikano, Kosuge Kotoko, Aoi Noriko, Matsumoto Koichi
Abstract excerpt
BACKGROUND AND OBJECTIVES: SAH has been proposed as a candidate gene for essential hypertension (EH) because elevated expression of SAH was observed in the kidneys of spontaneously hypertensive rats. Recently, a homology search of SAH in the human genome revealed the presence of the SAH gene family, which includes SAH, MACS1, MACS2, and MACS3. SAH and MACS1 are located within a 150-kb region on human chromosome...
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