Article
An acyl-CoA synthetase gene family in chromosome 16p12 may contribute to multiple risk factors.
Hypertension (Dallas, Tex. : 1979) - 1 May 2003
Iwai Naoharu, Mannami Toshifumi, Tomoike Hitonobu, Ono Koh, Iwanaga Yoshitaka
Abstract excerpt
We recently reported that genetic polymorphisms of SAH, an acyl-CoA synthetase for fatty acids, might contribute to multiple risk factors, especially hypertriglyceridemia. There are at least 4 members in this SAH gene family, SAH, MACS1, MACS2, and MACS3, and these 4 members are clustered in human Ch16p12. It is possible either that the previously observed associations were due to linkage disequilibrium with...
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