Article
Association of E-cadherin and beta-catenin with metastasis in nasopharyngeal carcinoma.
Chinese medical journal - 1 Aug 2004
Li Zhi, Ren Yi, Lin Su-xia, Liang Ying-jie, Liang Hui-zhen
Abstract excerpt
BACKGROUND: This study was designed to detect methylation of E-cadherin gene promoter and gene mutation of beta-catenin in exon 3 and their expression of protein and mRNA in primary tumor and lymph node metastatic tumor of nasopharyngeal carcinoma (NPC), and investigate the mechanism of invasion and metastasis of neoplastic cells in NPC. METHODS: Fourty-two fresh biopsy samples were taken from untreated NPC...
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