Article
T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas.
Cancer science - 1 May 2009
Beder Levent Bekir, Gunduz Mehmet, Hotomi Muneki, Fujihara Keiji, Shimada Jun, Tamura Shinji, Gunduz Esra, Fukushima Kunihiro, Yaykasli Kursat, Grenman Reidar, Shimizu Kenji, Yamanaka Noboru
Abstract excerpt
Previous gene expression profiles revealed the T-lymphocyte maturation-associated protein (MAL) gene as being frequently downregulated in head and neck cancer. To define the relationship between the MAL gene and the metastatic process, we evaluated the expression status of the gene in matched primary and metastatic tumors of head and neck cancer by semiquantitative reverse transcription-polymerase chain reaction....
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