Article
Curcumin alters the migratory phenotype of nasopharyngeal carcinoma cells through up-regulation of E-cadherin.
Anticancer research - 1 Jul 2010
Wong Thian-Sze, Chan Wing-San, Li Chi-Han, Liu Raymond Wai-Man, Tang Whitney Wing-Yan, Tsao Sai-Wah, Tsang Raymond King-Yin, Ho Wai-Kuen, Wei William Ignace, Chan Jimmy Yu-Wai
Abstract excerpt
BACKGROUND: Curcumin is a natural polyphenol. It is a potent suppressor of nuclear factor kappa B (NF-kappaB). High NF-kappaB levels have suppressive effect on E-cadherin (molecule related to cell-cell adhesion) in nasopharyngeal carcinoma (NPC) cells. We hypothesized that suppressing NF-kappaB b...
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